What i've noticed that with Safari for Panther is that YTMNDs (little single comedy sites) that have centered .gif images in their code, will NOT load. Now I've asked friends that have used the newest one on Tiger, and they have said they work fine.
The example I gave was just a classic example, but it's everyone with centered .gif images.
Please don't file the exact same bug multiple times :)
*** This bug has been marked as a duplicate of 13703 ***