Go to python.org or open the attached WebArchive. In the fourth paragraph (the one that starts "The Python Software Foundation (PSF) holds...") try and create a selection that starts at the end of the paragraph. For example, click just after "community." and drag upward. The selection endpoint is somewhere after "Python conference" instead of after "community." <rdar://problem/6263677>
Created attachment 28000 [details] webarchive of the problematic page
Created attachment 28001 [details] A somewhat reduced testcase. Double click a couple pixels below the word "the"
FWIW, this is not a super-recent regression. Happens on the Safari 4 beta as well.
I don't know that it is a regression at all.
Created attachment 28054 [details] a better test case Firefox lets you click on the "clickhere" and puts the cursor inside that text, but if you click below it, then it puts the cursor inside the span that has the large blue bottom border. Not really sure what the preferred behavior is.
http://code.google.com/p/chromium/issues/detail?id=7755 is the Chromium bug.