This is hard to reproduce until introduction of blob usage in the inspector itself (https://bugs.webkit.org/show_bug.cgi?id=141405). We should be able to tell when blobs/files get GC'd, then remove tree elements for things that reference them (Fonts, Images). Right now we keep entries for all blobs (named after the objectURL created for the blob) even if the object URL is no longer valid.
<rdar://problem/19803964>
It turns out that Google Maps uses blobs + objectURLs for nearly all of its tile image data (probably coming over on a WebSocket...). This would be a good test case as well, since 100's of blobs are created and used as image src=.